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新型冠狀病毒恐讓男性不孕！研究證實：Covid-19會攻擊睪丸

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林以璿

2020年3月29日 下午12:31

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新冠肺炎疫情肆虐全球，有學者發表論文指出新冠肺炎損傷男性生殖功能、攻擊睾丸，以致性激素水平顯著改變。研究人員提醒醫護人員，應關注育齡男性患者的生殖功能。

有關研究由武漢大學中南醫院生殖醫學中心副教授張銘等人進行，近日在網站「MedRxiv」上傳的一篇論文，題為《新冠感染對男性性腺功能影響的單中心研究》（Effect of SARS-CoV-2 infection upon male gonadal function： A single center-based study），成為新冠肺炎損傷男性生殖功能的首個臨床證據。

新冠病毒可攻擊睾丸功能

研究對比81名武漢火神山醫院育齡男性新冠患者和100名年齡相仿的健康男性後發現，前者的血清促黃體生成素（LH）和催乳素水平顯著升高，而睪酮與卵泡刺激素相對LH的比值顯著降低。

LH是由腺垂體細胞分泌的一種糖蛋白類促性腺激素，可促進膽固醇在性腺細胞內轉化為性激素。論文指出，雖然精液參數才直接反映生殖腺功能，但上述指標的改變，也為新冠攻擊睾丸功能提供首個間接的臨床證據。

研究亦提到，新冠病毒攻擊細胞的靶點是簡稱為ACE2的受體血管緊張素轉換酶II。這個靶點並不僅僅出現在肺部，在睾丸中的蛋白質和mRNA表達幾乎是人體內最高的，包括間質細胞和輸精管細胞。

美國研究同樣證實：Covid-19攻擊睪丸

美國官方衛生研究院（NIH）旗下兩名學者也發表最新研究結果，指出男性人體睪丸中的精原細胞、間質細胞和支持細胞，都是新型冠狀病毒攻擊目標，如果遭到感染可能導致男性「生精」失敗。

過往研究也發現伊波拉、馬爾堡病毒也都曾在男性睪丸或精液中出現，並透過性傳播。HIV也可誘發睪丸炎甚至不孕症。

SARS病毒也會攻擊男性生殖器官

根據世界衛生組織（WHO）研究報導，SARS病毒感染後會攻擊男性睾丸組織，損傷睾丸內細胞，進而引起睾丸炎，同時對男性生育力造成重大影響，導致不孕不育，甚至引起睾丸腫瘤。 新冠病毒與SARS病毒同為冠狀病毒，有理由相信新冠同樣可能會對男性睾丸產生嚴重的損傷。

參考資料：Effect of SARS-CoV-2 infection upon male gonadal function: A single center-based study

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馬龍

武漢肺炎確診再添1死 40多歲男曾遊奧地利捷克

中央社

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The Central News Agency 中央通訊社

2020年3月29日 下午10:43

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（中央社記者陳偉婷台北29日電）中央流行疫情指揮中心今晚宣布，新增一名武漢肺炎確診患者死亡，為第108案，40多歲男性，曾到奧地利、捷克旅遊。目前全台武漢肺炎累計3死。（編輯：唐聲揚）1090329

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馬龍

【武漢肺炎】全球疫情大爆發 僅存北韓、南蘇丹20國「零確診」

上報

7.3k 人追蹤

追蹤

李靖棠

2020年3月29日 下午2:30

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26 則留言

新型冠狀病毒引發的肺炎（COVID-19）持續擴散，截至29日11時，全球確診病例為66萬3740例，累計死亡人數達30879人；中國全境確診病例達8萬2341例，死亡人數3306人；台灣目前確診283例，並出現2名死亡病例。

《新聞週刊》（Newsweek）報導，隨著全球肺炎疫情持續擴大升溫，確診和死亡病例數量也不斷增加，六大洲國家幾乎全面失守，現階段僅有不到20國，依然維持境內「零確診」的紀錄。

African News: These Are the Only Countries Still Not Reporting Any Coronavirus Cases https://t.co/Aw5K0mnG1v

— Trendard Global Trending News (@TrendardNews) March 28, 2020

報導中舉了5至6國為案例，其中第一例、也是距離台灣最近的一國，正是金正恩統治下的北韓，從全面鎖國和切斷國際交通之後，雖不斷傳出隔離、疑似案例的新聞，但至今為止、該國仍未通報一例確診感染的病例。

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除了全面鎖國，北韓也積極進行新醫院興建工程，並對各地展開消毒。（湯森路透）

亞洲國家中，維持零確診的還包含土庫曼（Turkmenistan）、塔吉克（Tajikistan）與中東的葉門。與伊朗有陸地接壤的土庫曼，第一時間仿效北韓的作法，全面封閉邊境、禁止公眾聚會和進行預防性隔離，才讓該國能免於疫情衝擊，甚至能寄送物資與裝備，幫助南部鄰居伊朗對抗疫情。

鄰近的塔克克也尚無確診，該國同樣採取嚴格鎖國和公眾聚會的限制，並且即時取消如耨儒孜節（Nowruz）般的大型節慶，降低群聚感染風險。

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面對新型肺炎的疫情，中東各國受伊朗波及，幾乎全面失守。（湯森路透）

至於中東的葉門，則是在敘利亞出現五起病例後，波灣區域唯一一個「零確診」的國家，但深陷內戰多年的它，似乎並非控管得宜，而是政府無力進行檢疫，才呈現零通報的狀態。

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南太平洋海域則因地理位置，多數島國仍未受到疫情波及，包含庫克群島、馬歇爾群島、索羅門群島、諾魯、密克羅尼西亞、帛琉、薩摩亞、萬那杜和吐瓦魯等都維持「零確診」狀態。

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非洲大陸也面臨疫情擴散威脅，南非政府已下令軍隊進駐管制，控管人員流動和進行宵禁。（湯森路透）

如將眼光轉移到國家數量最多的非洲，當地疫情擴散速度相當迅速，現階段只有蒲隆地（Burundi）、賴索托（Lesotho）、獅子山共和國（Sierra Leone）、葛摩（Comoros）、南蘇丹、聖多美普林西比（São Tomé and Príncipe）和馬拉威（Malawi）尚無確診出現。

但正如上述提及的葉門，剛剛從長年內戰脫身的南蘇丹，國內醫療系統薄弱、教育程度不高和公共衛生條件不佳，讓許多專家和國際組織擔憂，稍有不慎、當地很可能成為非洲疫情的破口之一。

#COVID19 Surveillance Update: 28 March 2020 5:00pm EAT - https://t.co/wkbk2LdJuI
46 African Countries reporting a total 3,977 cases, 117 deaths, and 286 recoveries#FactsNotFear #AfricaPrepares #AfricaResponds pic.twitter.com/vvU33DukSQ

— African Union (@_AfricanUnion) March 28, 2020

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馬龍

新冠肺炎今新增7境外移入1本土共8例 死亡再增2例累計5例

Yahoo奇摩（即時新聞）

61.3k 人追蹤

追蹤

2020年3月30日 下午2:09

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274 則留言

新冠肺炎台灣確診今天突破300例！中央流行疫情指揮中心今天宣布，新增8例（2019冠狀病毒疾病，COVID-19）確診個案，目前全台累計306例，另新增2死亡案例；不過今天確診，亦再降為個位數。

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新冠肺炎今新增7境外移入1本土共8例 死亡再增2例累計5例

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新冠肺炎今新增7境外移入1本土共8例 死亡再增2例累計5例。（檔案照）

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中央流行疫情指揮中心指揮官陳時中今天表示，新增８例中，7例境外移入，1例本土，另新增2死，已累計5死。

指揮中心陳時中表示，今日新增7例境外移入個案為3女4男，年齡20多歲至70多歲，入境日介於3月2日至22日，發病日介於3月6日至26日；個案發病前活動地包括英國、美國、菲律賓與埃及，其中5人與群聚事件相關。

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馬龍

口罩限購放寬！成人14天9片「不分單雙號」隨時可買

TVBS新聞網

40.7k 人追蹤

追蹤

王雅惠

2020年3月30日 下午2:51

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19 則留言

指揮中心宣布口罩自下月9日起不分單雙號隨時可買。(圖／TVBS)

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針對口罩實名制，政府再做滾動式檢討，為讓民眾購買口罩更加方便，中央流行疫情指揮中心今(30日)宣布，4月9日起藥局不分單、雙號，隨時都可購買口罩，成人14天可買9片，兒童14天10片，可任選成人或兒童，但政府仍呼籲大家撙節使用。

口罩限購再放寬。(圖／衛生福利部)

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指揮中心今宣布，自4月9日起，不限身分證健保卡單、雙號，民眾可任選成人或兒童購買，購買後隔14天才能再次購買。舉例來說，4月9日購買後，下次購買時間為4月23日。小孩原為7天5片，改為14天10片；大人原為7天3片，改為14天9片。民眾可自由選擇要購買大人口罩或小孩口罩，不受年齡限制。

此外，先前政府禁止口罩出口如今也放寬，若要寄口罩給海外親屬，政府放寬可寄給二等親內家屬，限2個月內一次30片。指揮中心表示，時間會拉比較長是因為郵遞費用高昂，部分航空也沒有送件，考量國人方便一次放寬。

日前上路的「口罩實名制2.0」網路預購廣受好評，行政院近日再研擬推出「口罩3.0」，目前研擬方向希望能讓民眾可持健保卡、身分證及信用卡等，至4大超商插卡連線，就能立刻買到口罩，既快速又方便，不過詳細做法仍待行政院確定後公告。

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馬龍

馬龍

馬龍

台灣新冠肺炎新增7例境外移入、累計329例 均自英、美返國

Yahoo奇摩（即時新聞）

61.7k 人追蹤

追蹤

2020年4月1日 下午2:13

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267 則留言

新冠肺炎(武漢肺炎)延燒，指揮中心今天宣布台灣新增7例境外移入病例，均自美、英返國，為3男4女，年齡20多歲至70多歲，居住區域為北部4人、南部3人，發病日介於2月29日至3月27日。目前累計329例確診，分別為283例境外移入及46例本土病例；確診個案中5人死亡，45人解除隔離，其餘持續住院隔離中。

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新冠肺炎(武漢肺炎)延燒，指揮中心今天宣布台灣新增7例境外移入病例，均自美、英返國，為3男4女，居住區域為北部4人、南部3人，發病日介於2月29日至3月27日。(取自中央流行疫情指揮中心記者會直播)

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指揮中心表示，今日新增個案中，案325及329於2月6日至3月30日與另1名友人至美國自助旅遊，案325於3月23日出現嗅覺喪失情形，案329則於3月24日出現味覺及嗅覺喪失、有痰等症狀，2人返國入境時主動聲明有症狀，由機場檢疫人員採檢通報，於今日確診，為國外旅遊群聚感染；2名確診個案的另1名同行友人無疑似症狀，居家隔離中。

指揮中心指出，其餘5名境外移入病例為獨立個案，出國目的包括就學、工作及探親，發現管道為居家檢疫(2人)及機場(3人)。

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馬龍

全球破90萬人確診武漢肺炎 逾4.5萬人染疫喪命

中央社

16.7k 人追蹤

追蹤

The Central News Agency 中央通訊社

2020年4月2日 上午4:31

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留言

（中央社巴黎2日綜合外電報導）法新社使用官方來源統計，截至台灣時間今天凌晨3時，全球2019冠狀病毒疾病（COVID-19，武漢肺炎）官方確診人數已超過90萬例，超過4萬5000人感染死亡。

法新社報導，全球187個國家地區累計至少90萬5589人染病，其中4萬5719人死亡。

疫情快速擴散的美國確診達20萬3608例、死亡4476例。義大利共有11萬574人確診，死亡人數1萬3155人排各國之首。

西班牙共10萬2136人確診、9053人死亡。中國確診為8萬1554例、3312人死亡。（譯者：楊昭彥）1090402

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馬龍

警告全球確診將破百萬！世衛：新冠病毒是全體人類真正的威脅

鉅亨網

1.8k 人追蹤

追蹤

鉅亨網編譯羅昀玫

2020年4月2日 上午5:07

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188 則留言

世界衛生組織官員週三 (1 日) 表示，新冠病毒是全體人類真正的威脅，預告未來幾天將有超過 100 萬人染疫，死亡數將超過 5 萬人。

武漢肺炎 (COVID-19) 已蔓延全球超過 205 個國家，全球確診已超過 93 萬例，造成至少 4.6 萬人死亡，美國確診飆破 20 萬例。

全球超過 205 個國家出現確診病例。(圖片：CDC)

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世衛秘書長譚德塞表示：「過去五週，新增確診近乎呈指數級增長，過去一週內，死亡數就翻一倍以上… 未來幾天內，我們預測全球確診將超過 100 萬人、5 萬人死亡。」

世衛新發疾病主管克爾科夫 (Maria Van Kerkhove) 博士警告：「武漢肺炎是一個真正的威脅。這對地球上的每一個人都是真正的威脅。」

世界衛生組織 (WHO)、世界銀行 (WB)、和國際貨幣基金組織（IMF）週三 (1 日) 宣布，將支持發展中國家債務減免，以應對疫情帶來的社會、經濟衝擊。

譚德塞稱：「許多發展中的國家，無法完全支持社會，尤其是在封國 / 封城期間，這就是為什麼我們呼籲要對其減免債務… 我們建議加快腳步，支援這些國家，使他們的經濟不陷入危機，他們的社區不陷入危機

世衛組織突發衛生事件規劃執行主任 Mike Ryan 博士表示：「各國元首需要建立公衛系統，如果我們要擺脫一個經濟上懲罰性封鎖、停止無休止的循環，我們就必須重新掌控這類病毒、與其共存，研發出最終根除病毒的疫苗。」

聯合國 (UN) 秘書長古特瑞斯 (Antonio Guterres) 週三提到：「武漢肺炎是自聯合國成立以來，我們共同面臨的最大考驗。」

聯合國警示，疫情將對各國經濟造成沉重的長期影響，呼籲各國遵循世衛指導方針，並立即採取健康對策以遏制病毒的傳播，包括加強測試、隔離和治療。

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